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ABCDEFs of Prevention and Safety

ABCDEF is a standard bundle of ICU measures that includes spontaneous Assess for and manage pain, Both Spontaneous Awakening Trials (SAT) & Spontaneous Breathing Trials (SBT), attention to the Choice of sedation and analgesia, Delirium monitoring and management, Early mobility, and Family engagement. All individual components of this bundle are evidence based and can help standardize communication, improve interdisciplinary patient care, reduce mortality, and improve long-term cognitive and functional outcomes. This bundle helps to keep patients and families as the center and focus of care.

Patients and Aging Brain Problems:
Wes Ely Speaks about what drives this group’s work

Delirium in the News


Words that heal: ICU journals at Penn help patients and staff
The Philadelphia Inquirer
The Overlooked Danger of Delirium in Hospitals
The Atlantic


Dr. Robert C. Hyzy: Two minute video on culture and ABCDEF Bundle
MedPage Today
ICU liberation: Optimizing quality and efficiency of critical care delivery
Becker's Healthcare
Hospital Delirium
Second Opinion TV
Why a stay in the ICU can leave patients worse off
PBS Newshour
Nashville VA receives top honors for ICU care
Fox News Nashville
With Fewer Meds, More Movement, Parkland Hospital Fights ‘Delirium’ Among ICU Patients
These People Left The ICU With A Terrifying New Problem; What You Need To Know About PICS
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Delirium May Speed Up Cognitive Decline in Dementia


'ICU delirium' is terrifying — and incredibly common
The Week
Hospitals struggle to address terrifying and long-lasting ‘ICU delirium’
Intensive Confusion
Die Welt (German)
Patients at High Risk for Psychiatric Symptoms After a Stay in the ICU
DG News
More Common and More Harmful Than Once Believed, Delirium Takes Center Stage
Science of Caring - University of California San Francisco
10% of ICU Patients At Risk of Developing PTSD


Veterans, Civilian Patients at Risk of ICU-related PTSD up to a Year Post Discharge
Science Daily
ICU Recovery Center helps ease burden of critical illness
Vanderbilt University Medical Center Reporter
Dr. Wes Ely reads story about an ICU patient that was initially published in the Wall Street Journal
Our American Network (radio)
The Perils of Delirium
The Washington Post
More News

Support the Research

what is Delirium?

Delirium is basically inattention and confusion that represents the brain temporarily failing. A person who is delirious is unable to think clearly and can’t make sense of what is going on around him.

Delirium increases the risk of longer stays in the hospital, higher cost of care, death, and more long-term cognitive impairment up to one year later.

More Info for Medical Professionals More Info for Patients and Families

More Information on Delirium Assessment

For resources and education materials for delirium assessment, including the CAM-ICU, the bCAM, and the pCAM-ICU, visit the Delirium Monitoring page. For a complete list of all the materials available for download visit our comprehensive resources page.